QUB — Markov simulation and analysis for single molecules and ensembles

Quick start: QUB Online Fitness X-Means Movie Maker

The X-Means web app computes the AIC from:

• \(N_d\) - number of data points
• \(N_f\) - number of free parameters \(= 3 * K * N_{var}\)
• SSD - sum squared difference from the respective means

$$AIC = N_d ln (\frac{SSD}{N_d}) + 2 N_f$$

We use the AICc correction for small numbers:

$$AICc = AIC + (\frac{2 N_f(N_f + 1)}{N_d - N_f - 1})$$